Effects of cardiovascular drugs on the eyeball
Keywords:
Cardiovascular Agents/ adverse effects, Cardiovascular Agents/ contraindications, Eye Diseases/ chemically induced, Eye Diseases/ etiologyAbstract
Introduction and Objective: There is a high incidence of cardiovascular conditions among the patients who visit the ophthalmology offices, and many of drugs used for these conditions may cause undesirable effects on the eyeball. The objective of this research was to determine the adverse reactions caused by the consumption of these drugs in the visual organ, and highlight their contraindications in people affected by eye disease.
Method: A literature search was performed using specialized texts, and the drugs that could produce ocular adverse reactions were identified, as well as those that were contraindicated in ophthalmic diseases.
Results: A total of 276 medications were reviewed and 72 (26.08%) were selected. Blurred vision (38/72), decreased visual acuity (21/72) and dizziness (16/72) were the
most common adverse reactions associated with the use of cardiovascular drugs. The six medications that are contraindicated in these patients are exposed, as well as the 14 that should be prescribed with extreme caution in diseases such as glaucoma, optic atrophy, hypertensive retinopathy and migraine, among others.
Conclusions: It was found that 72 drugs (26.08%) used in cardiovascular disease may produce some ocular symptoms as an adverse reaction. Blurred vision, decreased visual acuity and dizziness were predominant. It is extremely important to conduct a good medical interview to know the patient's medical history and avoid the use of
drugs that are useful for a disease but harmful for another one. The doctor, knowingly, will weigh the risk/benefit of those drugs that are essential.
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References
1. Ministerio de Salud Pública, Dirección Nacional de Epidemiología. Controles de foco en la atención primaria de salud. La Habana: MINSAP; 2007.
2. Romero AF, Henríquez RD. Medicamentos, salud, empresas transnacionales. Derecho de la propiedad intelectual. Una perspectiva para los países en desarrollo. Rev Cubana Farm [Internet]. 2002 [citado 28 Mayo 2010];36 [Suplemento Especial No. 1]. Disponible en:http://www.uh.cu/centros/cesbh/Archivos/bvirtual/Antonio1.pdf
3. Alfonso Orta I, Alonso Carbonell l, Alonso Galván P, Calvo Barbado DM, Cruz barrios MA, Delgado Martínez I, et al. Formulario nacional de medicamentos [Internet]. La Habana: ECIMED; 2011 [citado 28 Mayo 2010]. Disponible en: http://www.bvs.sld.cu/libros_texto/formulario_medicamentos/formulario_med_completo01.pdf
4. Pérez Hernández BG. Reacciones adversas a los medicamentos y adición a otras sustancias. En:Morón Rodríguez RF, Levy Rodríguez M, Álvarez Corredera M, Borroto Regalado R, Cruz Barrios MA, Salazar Domínguez LE, et al. Farmacología General [Internet]. La Habana: ECIMED; 2002 [citado 28 Mayo 2010]:124-38. Disponible en: http://bvs.sld.cu/libros_texto/farma_gral/farmageneral.pdf
5. Negrín Díaz A, Garbey Villalón J, Cañet Prades J, Pérez Guerra M, Pérez Rodríguez A, Yenochik Lima N, et al. Medicamentos que actúan sobre el sistema cardiovascular. En: Farmacología. [Internet]. La Habana: ECIMED; 2001. p. 96-112 [citado 28 Mayo 2012]. Disponible en:http://bvs.sld.cu/libros_texto/farmacologia/farmcap_vii.pdf
6. Kuschinsky G, Lüllmann H, Vallvé C. Manual de farmacología. 3ra ed. La Habana: Instituto Cubano del Libro; 1967.
7. Beers MH, Porter RS, Jones TV, Kaplan JL, Berkwits M, editors. Trastornos cardiovasculares. En: El Manual Merck. 11na ed. España: Elsevier; 2007. p. 649-776, 803-10.
8. Rosenstein E. Diccionario de especialidades farmaceúticas. 41 ed. Agentes cardiovasculares. México: Ediciones PLM; 1995.
9. Aguilar Pacín N. Enfermedades cardiovasculares. En: Manual de terapéutica de medicina interna [Internet]. La Habana: ECIMED; 2007. p. 1-111 [citado 28 Mayo 2010]. Disponible en: http://www.bvs.sld.cu/libros/manual_terap_med_interna/cap1.pdf
10.Roca Goderich R, Smith Smith VV, Paz Presilla E, Losada Gómez J, Serret Rodríguez B, Llamos Sierra N, et al. Recuento anatomofisiológico del sistema circulatorio. En: Temas de Medicina Interna [Internet]. 4ta ed. La Habana: ECIMED; 2002. p. 239-529 [citado 28 Mayo 2010]. Disponible en: http://www.bvs.sld.cu/libros_texto/medicina_interna/tomo.pdf
11.Pérez Caballero MD, Vázquez Vigoa A, Cordiés Jackson L. Enfermedades cardiovasculares. En: Alfonso Fernández LA, Arce Hidalgo B, Areu Regateiro A, Argüelles Zayas AC, Argudín Depestre SG, Arús Soler E, et al. Manual de diagnóstico y tratamiento en especialidades clínicas [Internet]. La Habana: OPS; 2002. p. 26-78 [citado 28 Mayo 2012]. Disponible en: http://bvs.sld.cu/libros/manual_diagnostico/cap1.pdf
12.Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Hypertension [Internet]. 2003 [citado 28 Mayo 2012]42(6):[aprox. 5 p.]. Disponible en:http://hyper.ahajournals.org/content/42/6/1206.full
13.Matarama Peñate M, Llanio Navarro R, Muñiz Iglesias P, Quintana Setién C, Hernández Zúñiga R, Vicente Peña E. Enfermedades del sistema cardiovascular. En: Medicina Interna. Diagnóstico y tratamiento [Internet]. La Habana: ECIMED; 2005 [citado 28 Mayo 2012]. Disponible en: http://www.bvs.sld.cu/libros_texto/medicina_interna_diagnostico_tratamiento/completo.pdf
14.Reacciones oculares adversas a la farmacoterapia sistémica. Rev Cubana Med Gen Integr [Internet]. 1997 [citado 28 Mayo 2012];13(4):[aprox. 4 p.]. Disponible en:http://bvs.sld.cu/revistas/mgi/vol13_4_97/mgi13497.htm#14
15.Marino BS, Bird GL, Wernovsky G. Diagnosis and management of the newborn with suspected comgenital heart disease. Clinics in Perinatol 2001; 28: 91-136.
16.Lemus Lanziano JE, García del Río C, Urina Triana M. Cuidado crítico cardiovascular. Bogotá: Sociedad colombiana de Cardiología; 2010.
17.Furones Mourelle JA. Enfermedades cardiovasculares. En: Cires Pujol M, Delgado Martínez I, Cruz Barrios MA, Pérez Peña JL, Benítez Maqueira B, Calvo Barbado DM, et al. Guía terapeútica para la atención primaria de salud [Internet]. La Habana: ECIMED; 2010. p. 49-77 [citado 28 Mayo 2012]. Disponible en:http://www.bvs.sld.cu/libros/guia_terapeutica_aps/cap02.pdf
18.Alfonzo Guerra JP. Hipertensión arterial en la atención primaria de salud [Internet]. La Habana: ECIMED; 2009 [citado 28 Mayo 2012]. Disponible en: http://www.bvs.sld.cu/libros/hipertension_arterial/completo.pdf
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