First attempts to obtain predictive indexes in adolescent hypertension
Keywords:
hypertension, prehypertension, adolescent, forecastingAbstract
Introduction and Objectives: There are many risk factors for developing hypertension. In the XXI century, smarter ways to investigate are needed, so preventing the turning of an adolescent into a hypertensive adult must be a priority. The aim of this paper is to predict the risk of hypertension onset in adulthood, from cardiovascular tension and risk stratification since adolescence. Methods: A representative sample of 125 adolescents from the project PESESCAD-HTA was studied. They were diagnosed with prehypertension in 2001, and were followed for 8 years (96 months) until January 2009. Results: Two predictive indexes were obtained. The first, based on the total cardiovascular risk and the second from the multiplication of these risks with an accuracy index for each of 61.6% and 70.4%, respectively. Conclusions: The index based on the multiplication of cardiovascular risk can predict, with adequate accuracy, the turning of a prehypertensive adolescent into hypertensive once he/she reaches adulthood.
Downloads
References
1. Mancia G, Grassi G; European Society of Hypertension; European Society of Cardiology. Joint National Committee VII and European Society of Hypertension/European Society of Cardiology guidelines for evaluating and treating hypertension: a two-way road? J Am Soc Nephrol. 2005;16 (Suppl 1):S74-7.
2. Chobanian AV. Does It Matter How Hypertension Is Controlled? N Engl J Med. 2008;359(23):2485-88.
3. Pérez Caballero D, Dueñas Herrera A, Alfonzo Guerra J, Vásquez Viguoa A, Navarro Despaigne D, Del Pozo Pérez A, et al. Guía Cubana para la Prevención, Diagnóstico, y Tratamiento de la Hipertensión Arterial. La Habana: ECIMED; 2008.
4. Ingelfinger JR. Blood-pressure control and delay in progression of kidney disease in children. N Engl J Med. 2009;361(17):1701-3.
5. Dawson JD, Sonka M, Blecha MB, Lin W, Davis PH. Risk Factors Associated With Aortic and Carotid Intima-Media Thickness in Adolescents and Young Adults. The Muscatine Offspring Study. J Am Coll Cardiol. 2009;53(24):2273-9.
6. Lucini D, Zuccotti G, Malacarne M, Scaramuzza A, Riboni, S, Palombo C, et al. Early progression of the autonomic dysfunction observed in pediatric type 1 diabetes mellitus. Hypertension. 2009;54(5):987-94.
7. Lurbe E, Cifkova R, Cruickshank K, Dillon MJ,Ferreira I, Invitti C, et al. Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension. J Hypertens. 2009 Sep;27(9):1719-42.
8. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114(2):555-76.
9. Aglony M, Acevedo M, Ambrosio G. Hypertension in adolescents. Expert Rev Cardiovasc Ther. 2009;7(12):1595-1603.
10. Richey PA, Disessa TG, Hastings MC, Somes GW, Alpert BS, Jones DP. Ambulatory blood pressure and increased left ventricular mass in children at risk for hypertension. J Pediatr. 2008;152(3):343-8.
11. Di Bello V, Talini E, Dell'Omo G, Giannini C, Delle Donne MG, Canale ML, et al. Early left ventricular mechanics abnormalities in prehypertension: a two-dimensional strain echocardiography study. Am J Hypertens. 2010;23(4):405-12.
12. Everett CJ, Frithsen IL. Evidence that prehypertension is a risk factor for Type 2 diabetes. Expert Rev Cardiovasc Ther. 2010;8(3):335-33.
13. Pérez Fernández GA. Estrés e hipertensión arterial. Resultados del proyecto de investigación PESESCAD-HTA. Med Gen. 2001;38:818-22.
14. Pérez Fernández GA. Algunas variables-riesgos y su influencia sobre las cifras de tensión arterial en la adolescencia. Medicentro Electrónica [Internet]. 2001 [citado 3 Mar 2009];5(3):[aprox. 6 p]. Disponible en: http://www.vcl.sld.cu/medicentro/V5n301/algunas.htm
15. Pérez Fernández GA. Origen fetal de la enfermedad cardiovascular. La hipertensión arterial como paradigma. Rev Lat Cardiol. 2002;23(5):152-8.
16. Harper PR. A review and comparison of classification algorithms for medical decision making. Health Policy. 2005;71(3):315-31.
17. Kaplan NM. Combination therapy for hypertension. Nat Rev Cardiol. 2009;6(4):270-1.
18. Lenfant C, Roccella EJ. A call to action for more aggressive treatment of hypertension. J Hypertens Suppl. 1999;17(1):S3-7.
Downloads
Published
How to Cite
License
Copyright (c) 2011 CorSalud
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
