P−wave dispersion in hypertensive children; its relationship with body weight
Keywords:
P wave, hypertesion, body weight, obesityAbstract
Introduction and Objective: Atrial fibrillation is the paradigm of atrial electrical heterogeneity. The prolongation of intra and interatrial conduction and inhomogeneous propagation of electrical impulses are electrophysiological characteristics in paroxysmal atrial fibrillation. Obesity is a potential risk factor for atrial fibrillation. There are some reports about higher values of P wave dispersion in obese women. The aim was to determine the relationship between P wave dispersion and body weight in normotensive and hypertensive children between 8 and 11 years old. Method: 358 children from a total of 543 were studied. Those whose parents did not want them to participate in the study and those who had known congenital diseases were excluded. A 12-lead surface ECG and 4 blood pressure measurements were conducted. Maximum and minimum P values were measured and P wave dispersion in the electrocardiogram was calculated. Other variables such as body weight were also obtained. Results: The difference between mean values for P-wave dispersion between normotensive and hypertensive patients was 31.85 ms vs 39.74 ms, respectively, p <0.001. There was an increased dispersion of P wave with weight gain, r = 0.18 p = 0.05. Conclusions: In hypertensive patients, P-wave dispersion and weight show a significant correlation since childhood. There are significant differences between P wave dispersion values of the electrocardiogram between normotensive and hypertensive populations since childhood.
Downloads
References
Wang C, Xie ZW, Li MX. Analysis of P interval dispersion and its correlative factors among Chinese. Hunan Yi Ke Da Xue Xue Bao. 2001;26(3):241-3.
Dilaveris P, Stefanadis C. P wave dispersion: A valuable non-invasive marker of vulnerability to atrial fibrillation. Proceedings of the 2nd ISHNE Atrial Fibrillation Worldwide Internet Symposium; 2007 April 1-30. London: St. Jude Medical; 2007. Disponible en: http://af-symposium.grupoakros.com.ar/2007/lectures/ing_dilaveris_polychronis.pdf
Taggar JS, Lip GY. Risk predictors for lone atrial fibrillation. European Society of Cardiology. Europace. 2008;10(1):6-8.
Dilaveris PE, Gialafos JE. P-wave dispersion: a novel predictor of paroxysmal atrial fibrillation. Ann Noninvasive Electrocardiol. 2001;6(2):159-65.
Gur M, Yilmaz R, Demirbag R, Akyol S, Altiparmak H. Relation between P-wave dispersion and left ventricular geometric patterns in newly diagnosed essential hypertension. J Electrocardiol. 2008;41(1):54.e1-6.
Frost L, Hune LJ, Vestergaard P. Overweight and obesity as risk factors for atrial fibrillation or flutter: The Danish Diet, Cancer, and Health Study. Am J Med. 2005;118(5):489-95.
Seyfeli E, Duru M, Kuvandiık G, Kaya H, Yalcin F. Effect of obesity on P wave dispersion and QT dispersion in obese women. Int J Obes. 2006;30(6):957-61.
National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents. Pediatrics. 2004;114(2 Suppl 4th Report):555-76.
Lurbe E, Cifkova R, Cruickshank JK, Dillon MJ, Ferreira I, Invitti C, et al. Manejo de la hipertensión arterial en niños y adolescentes: Recomendaciones de la Sociedad Europea de Hipertensión. Hipertensión. 2010;27(2):47-74.
Beevers G, Lip GY, O´Brien E. ABC of hypertension: The pathophysiology of hypertension. Clinical review. BMJ. 2001;322(7291):912-16.
Eijsbouts SC, Majidi M, van Zandvoort M, Allessie MA. Effects of acute atrial dilation on heterogeneity in conduction in the isolated rabbit heart. J Cardiovasc Electrophysiol. 2003;14(3):269-78.
De la Riva I. Control humoral de la presión arterial. En: Cingolani HE, Houssay AB. Fisiología Humana de Houssay. 7ma ed. Buenos Aires: El Ateneo. 2010. p. 342-46.
Serra JL, Bendersky M. Fibrilación auricular y sistema renina-angiotensina. Rev Fed Arg Cardiolg. 2009;38:123-31.
Köse S, Aytemir K, Sade E, Can I, Özer N, Amasyali B, et al. Detection of patients with hypertrophic cardiomyopathy at risk for paroxysmal atrial fibrillation during sinus rhythm by P-wave dispersion. Clin Cardiology. 2006; 26(9):431-4.
Pritchett AM, Jacobsen SJ, Mahoney DW, Rodeheffer RJ, Bailey KR, Redfield MM. Left atrial volume as an index of left atrial size: a population-based study. J Am Coll Cardiol. 2003;41(6):1036-43.
Cagirci G, Cay C, Karakurt O, Eryasar N, Acikel S, Dogan M. P-wave dispersion increases in prehypertension. Blood Press. 2009;18(1):51-4.
Olaz F, Berjón J. Valoración cardiológica del paciente hipertenso. An Sist Sanit Navar 1998;21(Supl 1):S39-53.
Köse S, Kılıç A, İyisoy A, Kurşaklıoglu H, Lenk MK. P wave duration and P dispersion in healthy children. Turk J Pediatr. 2003;45(2):133-35.
Hatziyiann A, Tsioufis K, Kallikazaros J, Stefanadis Ch. P-wave dispersion evaluated on ecg or 24h-ECG is a predictor of paroxysmal atrial fibrillation in essential hypertension. Rev Am J Hypertens. 2004;17(S1):149A-150A.
Morillas P, Pallarés V, Llisterri JL, Sanchis C, Sánchez T, Fácila L, et al. Prevalencia de fibrilación auricular y uso de fármacos antitrombóticos en el paciente hipertenso ≥ 65 años. El registro FAPRES. Rev Esp Cardiol. 2010;63(8):943-50.
Sari I, Davutoglu V, Ozbala B, , Baltaci Y, Yavuz S, et al. Acute sleep deprivation is associated with increased electrocardiographic P-wave dispersion in healthy young men and women. Pacing Clin Electrophysiol. 2008;31(4):438-42.
Babaoglu K, Altun G, Binnetoğlu K. P-wave dispersion and heart rate variability in children with mitral valve prolapse. Pediatr Cardiol. 2011;32(4):449-54.
Mora G. Evaluación electrocardiográfica y con Holter de la fibrilación auricular. Rev Colomb Cardiol. 2007;14(Supl 3):S76-82.
Lombardi F. ACE inhibitors and AF. The 3rd ISHNE Atrial Fibrillation Worldwide Internet Symposium; 2009 October 1-30. London: St. Jude Medical; 2009. Disponible en: http://af-symposium.grupoakros.com.ar/2009/lectures/ing_lombardi_federico.pdf
Kabutoya T, Ishikawa S, Ishikawa J, Hoshide S, Kario K; JMS Cohort Study Investigators Group. P-wave morphologic characteristics predict cardiovascular events in a community-dwelling population. Ann Noninvasive Electrocardiol. 2012;17(3):252-9.
Martín García A, Jiménez-Candil J, Hernández J, Martín García A, Martín Herrero F, Martín Luengo C. Morfología de la onda P y recurrencia tras cardioversión de fibrilación auricular aislada. Rev Esp Cardiol. 2012;65(3):288-98.
Downloads
Published
How to Cite
License
Copyright (c) 2012 CorSalud

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.