Giant teratocarcinoma of anterosuperior mediastinum
Abstract
Germ cell tumors are not so frequent; among them, teratomas are most common in the mediastinal location. Teratomas in young men are usually malignant (teratocarcinoma), with a gender ratio of 13.5:1, and an average age of 26 years. We describe the evolution of a 19-year-old man with a mediastinal tumor, with pulmonary metastases and intracardiac infiltration, successfully removed; whose most frequent symptoms were: dyspnea, retrosternal pain, fever, cough, weight loss and superior vena cava syndrome. The diagnosis was made by chest x-ray and computed tomography. Total removal of the tumor and metastases was achieved, as well as the intracardiac tumor, with tricuspid valve repair. The patient had a satisfactory outcome during the first follow-up year.Downloads
References
1. Arnault V, Beaulieu A, Lifante JC, Sitges Serra A, Sebag F, Mathonnet M, et al. Multicenter study of 19 aortopulmonary window parathyroid tumors: the challenge of embryologic origin. World J Surg. 2010;34(9):2211-6.
2. Esme H, Eren S, Sezer M, Solak O. Primary mediastinal cysts: clinical evaluation and surgical results of 32 cases. Tex Heart Inst J. 2011;38(4):371-4.
3. Fraser RS, Colman NC, Müller NL, Paré PD, eds. Synopsis of diseases of the chest. 3ra. ed. Philadelphia: WB Saunders; 2005.
4. Hutchinson CB, Wang E. Primary mediastinal (thymic) large B-cell lymphoma: a short review with brief discussion of mediastinal gray zone lymphoma. Arch Pathol Lab Med. 2011;135(3):394-8.
5. Ronson RS, Duarte I, Miller JI. Embryology and surgical anatomy of the mediastinum with clinical implications. Surg Clin North Am. 2000;80(1):157-69.
6. Díaz VM, Khosravi P, Hernández B, Encinas S, Arranz JA, Pérez-Manga G. Tumores germinales mediastínicos. An Med Interna. 2008;25(5):241-3.
7. Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest 2005;128(4):2893-909.
8. Moran CA, Suster S. Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer. 1997;80(4):681-90.
9. Mainieri-Hidalgo JA, Rees-Alpízar V, Gamboa-González I, Mainieri-Breedy M. Tumores de células germinales del mediastino. Experiencia con 29 pacientes. Acta Méd Costarric. 2013;55(3):128-31.
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