Lipoprotein(a) and fibrinogen as predictors of complications in patients with acute coronary syndrome

Authors

  • Pedro A. Carvajal Sánchez Hospital General Municipal Docente de Placetas. Villa Clara, Cuba.
  • Ana M. Correa Morales Cardiocentro Ernesto Che Guevara. Villa Clara, Cuba.
  • Luis M. Reyes Hernández Cardiocentro Ernesto Che Guevara. Villa Clara, Cuba.
  • Rosa E. Díaz Benítez Hospital Universitario Celestino Hernández Robau. Villa Clara, Cuba.
  • Enma M. González Rivera Hospital Universitario Celestino Hernández Robau. Villa Clara, Cuba.
  • Misleidis García Márquez Hospital Universitario Arnaldo Milián Castro. Villa Clara, Cuba.

Abstract

Introduction: Cardiovascular diseases are the cause of the largest number of annual deaths in the developped world, so they are considered a scourge on mankind; these include ischemic heart disease.
Objectives: To determine the value of lipoprotein(a), fibrinogen and fibrinogen-lipoprotein(a) index in predicting short-term complications in patients with acute coronary syndrome.
Method: A cross-sectional descriptive study was conducted in 115 patients admitted with acute coronary syndrome to the Dr. Celestino Hernández Robau Hospital in Santa Clara, from November 2012 to October 2013.
Results: The study included 43 female and 72 male patients. The most frequent risk factors included hypertension (70.43%), dyslipidemia (50.43%) and a family history of coronary artery disease (47.83%). Complications occurred in 39 patients (33.9%). Cut-off points were established at 4.50 g/L for fibrinogen, 341 mg/L for lipoprotein(a) and 1.50 for fibrinogen-lipoprotein(a) index, which showed a sensitivity of 89%, specificity of 94% and a predictive ability given by an odds ratio of 122. Therefore it was classified as having a very good predictive value.
Conclusions: The fibrinogen-lipoprotein(a) index showed an excellent predictive value for short-term complications in patients with acute coronary syndrome.

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Published

2015-10-11

How to Cite

1.
Carvajal Sánchez PA, Correa Morales AM, Reyes Hernández LM, Díaz Benítez RE, González Rivera EM, García Márquez M. Lipoprotein(a) and fibrinogen as predictors of complications in patients with acute coronary syndrome. CorSalud [Internet]. 2015 Oct. 11 [cited 2025 Sep. 21];7(4):275-84. Available from: https://revcorsalud.sld.cu/index.php/cors/article/view/75

Issue

Vol. 7 No. 4 (2015)

Section

ORIGINAL ARTICLES

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