Electrocardiographic analysis of the T peak-T end interval dispersion in acute myocardial infarction with ST-segment elevation

Authors

  • Raimundo Carmona Puerta Hospital Provincial Universitario Cardiocentro Ernesto Guevara
  • José M. Ercia Arenal Hospital Universitario Celestino Hernández Robau
  • Ramiro R. Ramos Ramírez Hospital Provincial Universitario Cardiocentro Ernesto Guevara
  • Gustavo Padrón Peña Hospital Provincial Universitario Cardiocentro Ernesto Guevara
  • Arnaldo Rodríguez León Hospital Universitario Celestino Hernández Robau
  • Elibet Chávez González Hospital Provincial Universitario Cardiocentro Ernesto Guevara
  • Juan M. Cruz Elizundia Hospital Provincial Universitario Cardiocentro Ernesto Guevara

Keywords:

electrocardiography, arrythmias cardiac, myocardial infarction, sudden death

Abstract

Introduction and objectives: Tpeak-Tend interval dispersion is a new electrocardiographic variable recently associated to the risk of malignant ventricular arrhythmias in Brugada syndrome but it has hardly been studied in the acute myocardial infarction with ST-segment elevation. That is why it was analyzed in this context. Methods: A cross-sectional study was carried out in which the electrocardiograms of 37 patients with ST-segment elevation myocardial infarctions and other 37 apparently healthy patients (regarding electrocardiographic variables that assess ventricular repolarization) were compared. Results: Highly significant differences were found (p < 0,001) when comparing patients with myocardial infarction (QT 416,9 ± 42,3; QTc 431,4 ± 36,2) with the healthy patients  (QT 441,2 ± 57,4 y QTc 477,6 ± 58,5) and significant differences (p < 0,05) in T peak-T end interval (37,2 ms vs. 21,6 ms). There was a significant correlation between QT and T peak-T end in the inferior and anteroseptal STEMI, which was doubly intense in the anteroseptal localization (r = 0,34 vs. r = 0,80). Conclusions: T peak-T end interval dispersion was significantly higher in patients who have suffered from acute myocardial infarction with ST-segment elevation, regardless infarction localization.

Downloads

Download data is not yet available.

References

1. Kinter L. B, Valentin J-P. Safety pharmacology and risk assessment. Fundamental Clin Pharmacol. 2002;16:175-82.

2. Antzelevitch C. Tpeak-Tend interval as an index of transmural dispersion of repolarization. Eur J Clin Invest. 2001;31(7):555-7.

3. Wolk R, Stec S, Kulakowski P. Extrasystolic beats affect transmural electrical dispersion during programmed electrical stimulation. Eur J Clin Invest. 2001;31(4):293-301.

4. Tanabe Y, Inagaki M, Kurita T, Nagaya N, Taguchi A, Suyama K, et al. Sympathetic stimulation produces a greater increase in both transmural and sapatial dispersion of repolarization in LQT1 than LQT2 forms of congenital long QT syndrome. J Am Coll Cardiol. 2001;37:911-9.

5. Frederiks J, Swenne CA, Kors JA, Van Herpen G, Maan AC, Levert JV, et al. Within-subjects electrocardiographic differences at equal heart rates: role of automatic nervous system. Pflugers Arch. 2001;441(5):717-24.

6. Pérez Riera AR, Schapachnik E, Dubner S, Baranchuk A. El valor del electrocardiograma en el diagnóstico de las enfermedades eléctricas primarias o canalopatías sin cardiopatía estructural aparente. Segunda parte: descripción del síndrome del QT prolongado, del QT corto y de la taquicardia ventricular polimórfica catecolaminérgica. Rev Fed Arg Cardiol. 2010;39(2):69-80.

7. Wang JF, Shan QJ, Yang B. Tpeak-Tend interval and risk of cardiac events in patients with Brugada syndrome. Zhonghua Xin Xue Guan Bing Za Zhi. 2007;35:629-32.

8. Zabel M, Lichtlen PR, Haverich A. Comparison of ECG variable of dispersion of ventricular repolarization with direct myocardial repolarization measurements in the human heart. J Cardiovasc Electrophysiol. 1998;9(12):1279-84.

9. Emori T, Antzelevitch C. Cellular basis for complex T waves and arrythmic following combined activity in I(Kr) and I(Ks) block. J Cardiovasc Electrophysiol. 2001;12(12):1379-80.

10. Antzelevitch C. Cardiac repolarization. The long and short of it. Europace. 2005;7:53-9.

11. Antzelevitch C, Oliva A. Amplification of spacial dispersion of repolarization underlies sudden cardiac death associated with catecholaminergic polimorphic VT, long QT, short QT and Brugada syndromes. J Intern Med. 2006;259:48-58.

12. Antzelevitch C. The role of spacial dispersion of repolarization in inhereted and acquired suden cardiac death síndromes. Am J Physiol. Heart Circ Physiol. 2007;293(4):2024-38.

13. Castro Hevia J, Antzelevitch C, Tornes Bárzaga F, Dorantes Sánchez M, Dorticos Balea F, Zayas Molina R, et al. Tpeak-Tend and Tpeak-Tend dispersion as risks factors for ventricular tachycardia/ ventricular fibrillation in patients with the Brugada syndrome. J Am Coll Cardiol. 2006;47:1828-34.

Downloads

Published

2010-09-06

How to Cite

1.
Carmona Puerta R, Ercia Arenal JM, Ramos Ramírez RR, Padrón Peña G, Rodríguez León A, Chávez González E, et al. Electrocardiographic analysis of the T peak-T end interval dispersion in acute myocardial infarction with ST-segment elevation. CorSalud [Internet]. 2010 Sep. 6 [cited 2025 Sep. 12];2(3):184-90. Available from: https://revcorsalud.sld.cu/index.php/cors/article/view/1126

Issue

Vol. 2 No. 3 (2010)

Section

ORIGINAL ARTICLES

Categories

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.