Complexity of coronary lesions in diabetic patients

Authors

  • Guillermo Pacheco González Hospital Militar Central “Dr. Luis Díaz Soto”
  • Ángel G. Obregón Santos Centro de Investigaciones Médico Quirúrgicas
  • Ronald Aroche Aportela Centro de Investigaciones Médico Quirúrgicas
  • Héctor Conde Cerdeira Centro de Investigaciones Médico Quirúrgicas
  • Myder Hernández Navas Hospital General Docente “Enrique Cabrera”
  • Julio C. Gandarilla Sarmientos Instituto de Cardiología y Cirugía Cardiovascular

Keywords:

diabetes mellitus, risk factors, coronary disease, angioplasty

Abstract

Introduction and Objectives: Coronary artery disease in diabetic patients is presented in a very aggressive form with excessive progression of atherosclerosis and increased risk of stent restenosis or thrombosis in percutaneous coronary intervention. The objective of this research was to determine the relationship between diabetes mellitus and certain characteristics of coronary lesions and their relation with restenosis, thrombosis and development of new lesions after percutaneous procedure. Method: A retrospective-descriptive study was performed. Out of  the 1,464 patients revascularized at the Medical and Surgical Research Center in Havana, Cuba, between August 1997and February 2009, 270 diabetic patients were selected. Results: Diabetes mellitus was a risk factor for the following lesions: circumflex (OR*=1.48); ostium aorto-coronary (OR=3.58), left anterior descending (OR=2.41)and circumflex (OR=4.89), and trunk lesions extending into the left anterior descending artery(OR=9.79). Diabetics were more likely to develop complex lesions type B2 and C (OR=1.36), for curves higher than 90º (OR = 3.03), with previous curves higher of 90º (OR=6.13), injuries of more than 20mm (OR=2.0), in branches (OR = 1.69)and injuries due to absence of coronary flow (OR=4.15). They were also characterized by having smaller arteries of 3 mm (OR=1.32) and increased risk of developing new lesions (OR=2.11), restenosis (OR=2.11) and thrombosis (OR=3.06) of stent. Conclusions: Diabetes mellitus was a risk factor for the development of complex coronary lesions with a high risk of further lesions, restenosis and stent thrombosis.

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Published

2012-06-01

How to Cite

1.
Pacheco González G, Obregón Santos Ángel G, Aroche Aportela R, Conde Cerdeira H, Hernández Navas M, Gandarilla Sarmientos JC. Complexity of coronary lesions in diabetic patients. CorSalud [Internet]. 2012 Jun. 1 [cited 2025 Oct. 2];4(2):92-6. Available from: https://revcorsalud.sld.cu/index.php/cors/article/view/1210

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Vol. 4 No. 2 (2012)

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ORIGINAL ARTICLES

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