Sternal reconstruction in a patient with postoperative mediastinitis
Keywords:
Postoperative mediastinitis; Sternal infection; Risk factors; Sternal reconstructionAbstract
Postoperative mediastinitis is a severe infection with an incidence of 0.5-3% and a mortality rate that can exceed 20%. This article presents the case of a 58-year-old woman with risk factors who developed this complication following mitral valve replacement, presenting with purulent drainage, sternal instability, and chest pain. Diagnosis is primarily based on clinical findings such as these, while factors like diabetes, COPD, and bilateral internal mammary artery harvesting increase the risk. Successful management required a multidisciplinary approach that combined aggressive surgical debridement, prolonged culture-guided antibiotic therapy, and definitive reconstruction using specialized techniques tailored to the defect classification, ultimately achieving resolution of the infectious process.
Downloads
References
Tymowski C de, Provenchère S, Para M, Duval X, Grall N, Sahnoun T, et al. Deep sternal wound infection after cardiac surgery: a combination of 2 distinct infection types, deep incisional surgical-site infection and mediastinitis: results of a retrospective study. Surgery. 2025;181. doi: 10.1016/j.surg.2025.109255
Pérez-Granda MJ, Bouza E, Barrio-Gutiérrez JM, Machado M, Estevez A, Cuerpo G, et al. Evolution of postsurgical mediastinitis after major heart surgery (MHS) in the last 12 years: are we improving? Rev Esp Quimioter. 2025;38(5):394-400. doi: 10.37201/req/041.2025
Bermúdez-Yera GJ. Mapas conceptuales para la toma de decisiones ante la mediastinitis postoperatoria [Internet]. CorSalud. 2025 [citado 2025 oct 4];17(1):e1151. Disponible en: https://revcorsalud.sld.cu/index.php/cors/article/view/1151
Bouza E, Alarcón A de, Fariñas MC, Gálvez J, Goenaga MÁ, Gutiérrez-Díez F, et al. Prevention, diagnosis and management of post-surgical mediastinitis in adults consensus guidelines of the spanish society of cardiovascular infections (SEICAV), the spanish society of thoracic and cardiovascular surgery (SECTCV) and the biomedical research centre network for respiratory diseases (CIBERES). J Clin Med. 2021;10(23):5566. doi: 10.3390/jcm10235566
Abdelnoor M, Sandven I, Vengen Ø, Risnes I. Mediastinitis in open heart surgery: a systematic review and meta-analysis of risk factors. Scand Cardiovasc J SCJ. 2019;53(5):226-34. doi: 10.1080/14017431.2019.1642508
Vinokurov IA, Belov YuV, Tagabilev DG, Yusupov SA. Postoperative sternomediastinitis: morphology of lesion, treatment strategy. Pirogov Russ J Surg. 2024;(7):78. doi: 10.17116/hirurgia202407178
Bayer N, Mark Hart W, Arulampalam T, Hamilton C, Schmoeckel M. Is the use of BIMA in CABG sub-optimal? A review of the current clinical and economic evidence including innovative approaches to the management of mediastinitis. Ann Thorac Cardiovasc Surg. 2020;26(5):229-39. doi: 10.5761/atcs.ra.19-00310
Martínez-Martín P, Rodríguez SR, Clement IM, Díez-Vidal A, Quiles-Melero I, Ramchandani B, et al. Post-surgical mediastinitis caused by Aspergillus calidoustus in a heart transplant recipient: A case report and review of the literature. Diagn Microbiol Infect Dis. 2025;112(2):116796. doi: 10.1016/j.diagmicrobio.2025.116796
Berjaoui N, Santos F, Curti F, Chan PS, Lampridis S, Patel A, et al. Surgical management of complex mediastinitis: an 8-year single-centre experience reinforcing the role of open thoracotomy. Interdiscip Cardiovasc Thorac Surg. 2025;40(7):ivaf154. doi: 10.1093/icvts/ivaf154
Ivert T, Berge A, Bratt S, Dalén M. Incidence and healing times of postoperative sternal wound infections: a retrospective observational single-centre study. Scand Cardiovasc J. 2024;58(1):2330349. doi: 10.1080/14017431.2024.2330349
Deng F, Yu A, Yang C, Yang G, Zhou D, Nie X, et al. Retrospective analysis of the positive effect of emergency room national early warning score 2 on descending necrotizing mediastinitis patients. BMC Cardiovasc Disord. 2025;25:320. doi: 10.1186/s12872-025-04773-x
Lepelletier D, Bourigault C, Roussel JC, Lasserre C, Leclère B, Corvec S, et al. Epidemiology and prevention of surgical site infections after cardiac surgery. Med Mal Infect. 2013;43(10):403-9. doi: 10.1016/j.medmal.2013.07.003
Pastene B, Cassir N, Tankel J, Einav S, Fournier PE, Thomas P, et al. Mediastinitis in the intensive care unit patient: a narrative review. Clin Microbiol Infect. 2020;26(1):26-34. doi: 10.1016/j.cmi.2019.07.005
Bermúdez Yera GJ, Barreto Fiu EE, Lagomasino Hidalgo ÁL, Naranjo Ugalde AM, López de la Cruz Y. Nueva clasificación clínica para la mediastinitis posoperatoria a partir del análisis multivariado de conglomerado y la opinión de expertos [Internet]. Rev Cuba Cardiol Cir Cardiovasc. 2023 [citado 2025 nov 17];29(2):e1431. Disponible en: https://revcardiologia.sld.cu/index.php/revcardiologia/article/view/1431
Nenna A, Nappi F, Dougal J, Satriano U, Chello C, Mastroianni C, et al. Sternal wound closure in the current era: the need of a tailored approach. Gen Thorac Cardiovasc Surg. 2019;67(11):907-16. doi: 10.1007/s11748-019-01204-5
Can B, Kırış YF, Dağ H, Güzel YÇ, Dolapoğlu A. Sternal wound types after median sternotomy and reconstruction using dead space-based approach. Turk J Thorac Cardiovasc Surg. 2024;32(3):261-70. doi: 10.5606/tgkdc.dergisi.2024.26053
Bertheuil N, Leclere FM, Bekara F, Watier E, Flécher E, Duisit J. Superior epigastric artery perforator flap for reconstruction of deep sternal wound infection. Microsurgery. 2021;41(5):405-11. doi: 10.1002/micr.30743
Argueta Caceres N, Bermúdez Yera GJ. Mastocutaneous rotational flap to repair tissue loss secondary to deep sternal wound infection. Plast Reconstr Regen Surg. 2025;4(1-2):30-3. doi: 10.57604/PRRS-1193
Goishi K, Harada H, Keyama T, Tsuda T, Hashimoto I. Pectoralis major turnover flap based on thoracoacromial vessels for sternal dehiscence. Microsurgery. 2020;40(2):137-44. doi: 10.1002/micr.30509
Greig AVH, Geh JLC, Khanduja V, Shibu M. Choice of flap for the management of deep sternal wound infection--an anatomical classification. J Plast Reconstr Aesthetic Surg JPRAS. 2007;60(4):372-8. doi: 10.1016/j.bjps.2006.10.005
Raman J, Song DH, Bolotin G, Jeevanandam V. Sternal closure with titanium plate fixation--a paradigm shift in preventing mediastinitis. Interact Cardiovasc Thorac Surg. 2006;5(4):336-9. doi: 10.1510/icvts.2005.121863
Marasco SF, Fuller L, Zimmet A, McGiffin D, Seitz M, Ch’ng S, et al. Prospective, randomized, controlled trial of polymer cable ties versus standard wire closure of midline sternotomy. J Thorac Cardiovasc Surg. 2018;156(4):1589-1595.e1. doi: 10.1016/j.jtcvs.2018.04.025
Barbera F, Lorenzetti F, Marsili R, Lisa A, Guido G, Pantaloni M. The Impact of Preoperative Negative-Pressure Wound Therapy on Pectoralis Major Muscle Flap Reconstruction for Deep Sternal Wound Infections. Ann Plast Surg. 2019;83(2):195-200. doi: 10.1097/SAP.0000000000001799
Downloads
Published
How to Cite
License
Copyright (c) 2026 Daniel Hernández-Torres, Gustavo de J. Bermúdez Yera, José R. Valdés-González, Roger Mirabal Rodríguez, Carlos A. Santana Santana, Eduardo Pérez Correa

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.





