Avances en el conocimiento de las bases moleculares y celulares de las cardiopatías congénitas. Parte 1 de 2: Morfogénesis cardíaca

Noel Taboada Lugo

Authors

Noel Taboada Lugo Centro Provincial de Genética Médica de Villa Clara http://orcid.org/0000-0002-1254-8087

Abstract

Congenital heart diseases are the most common congenital defect in humans. Many studies indicate that the cardiac development is tightly regulated by different cell signaling pathways and genetically controlled morphological events. The identification of new genes involved in the cardiogenesis process is very useful in order to know the molecular and cellular mechanisms by which the broad phenotypic spectrum of congenital heart disease is generated. An updated bibliographic review was carried out, with the aim of identifying the most recent advances in the knowledge of the molecular and cellular bases of congenital heart disease. This knowledge allows a more effective classification of these congenital defects and a future optimization of the individualized treatment for each patient, in addition to offering possible specific and susceptible points of intervention that would allow the prevention of some of these more frequent congenital defects in humans.

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Author Biography

Noel Taboada Lugo, Centro Provincial de Genética Médica de Villa Clara

Máster en Ciencias. Especialista de I y II Grado en Medicina General Integral. Especialista de I y II Grado en Genética Clínica. Profesor Auxiliar de Genética Médica. Centro Provincial de Genética Médica de Villa Clara.

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