Cardiometabolic vulnerability due to body adiposity and atherogenic indices in the short-term postpartum period
Abstract
Introduction: Excessive accumulations of adipose tissue are a threat to cardiometabolic health; their assessment in women would better inform about their metabolic state.
Objective: To identify associations between cardiometabolic vulnerability states and atherogenic indices in the short-term postpartum period.
Method: A descriptive observational study was conducted from January 2017 to August 2018 on 119 women in short-term postpartum. The study population consisted of 773 pregnant women with adequate weight and apparently healthy at the time of recruitment, who were classified based on their cardiometabolic vulnerability due to body adiposity at the Policlínico Chiqui Gómez Lubián, between January 2012 and December 2016. The association of cardiometabolic vulnerability with the atherogenic indices was studied: Castelli, Kannel and the TG/HDLc ratio. The Kruskal-Wallis test was applied to compare independent samples.
Results: The Castelli (3.37), Kannel (2.02) and TG/HDL (0.71) indices showed lower mean values in women without vulnerability. The Castelli (4.20) and Kannel (2.69) indices showed higher values in women with extreme global vulnerability due to high overall adiposity and high central adiposity. The TG/HDLc index (1.18) reached the highest values in women with global vulnerability due to intermediate and high central overall adiposity.
Conclusions: The values of the atherogenic indices studied in the short-term postpartum period were associated with cardiometabolic vulnerability, with higher figures in women with intermediate and high general adiposity, and high central adiposity. Cardiometabolic vulnerability due to body adiposity in the short-term postpartum period may alert about atherogenic metabolic disorders, such as cardiovascular risk.
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1. Padrón Chacón R, Fraga Díaz C, Oliva Linares JE. Obesidad y Síndrome Metabólico. En: El Síndrome Metabólico. La Habana: Editorial de Ciencias Médicas; 2019. p. 58-119.
2. Molina de Salazar D, Muñoz Gómez D. Síndrome metabólico en la mujer. Rev Colomb Cardiol. 2018;25(Supl 1):21-9. DOI: https://doi.org/10.1016/j.rccar.2017.12.006
3. Irecta Najera CA, Álvarez Gordillo GC. Mecanismos moleculares de la obesidad y el rol de las adipocinas en las enfermedades metabólicas. Rev Cuban Invest Bioméd [Internet]. 2016 [citado 19 Jun 2020];35(2):174-83. Disponible en: http://scielo.sld.cu/pdf/ibi/v35n2/ibi06216.pdf
4. Orozco Muñoz C, Cañizares Luna O, Sarasa Muñoz N. Estado nutricional, acumulación de tejido adiposo y vulnerabilidad cardiometabólica en gestantes sanas de peso adecuado. Gac Méd Espirit [Internet]. 2018 [citado 20 Jun 2020];20(2):40-7. Disponible en: http://revgmespirituana.sld.cu/index.php/gme/article/view/1701/pdf
5. Orozco Muñoz C, Sarasa Muñoz NL, Hernández Díaz D, Cañizares Luna O, Álvarez Guerra E, Artiles Santana A. Indicadores antropométricos para la caracterización de la adiposidad corporal en gestantes sanas al inicio del embarazo. CorSalud [Internet]. 2018 [citado 23 Jun 2020];10(4):274-85. Disponible en: http://www.revcorsalud.sld.cu/index.php/cors/article/view/396/781
6. Castelli WP. Epidemiology of coronary heart disease: the Framingham study. Am J Med. 1984;76(2A):4-12. DOI: https://doi.org/10.1016/0002-9343(84)90952-5
7. Millán J, Pintó X, Muñoz A, Zúñiga M, Rubiés Prat J, Pallardo LF, et al. Cocientes lipoproteicos: significado fisiológico y utilidad clínica de los índices aterogénicos en prevención cardiovascular. Clin Invest Arterioscl. 2010;22(1):25-32. DOI: http://dx.doi.org/10.1016/S0214-9168(10)70005-X
8. McLaughlin T, Reaven G, Abbasi F, Lamendola C, Saad M, Waters D, et al. Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease? Am J Cardiol. 2005;96(3):399-404. DOI: https://doi.org/10.1016/j.amjcard.2005.03.085
9. García Alonzo L, Carías Picón D, Acosta García E. Factores de riesgo cardiovascular lipídicos y no lipídicos en una población adulta. Acta Bioquím Clín Latinoam. 2016;50(4):609-22.
10. Okosun IS, Okosun B, Lyn R, Airhihenbuwa C. Surrogate indexes of insulin resistance and risk of metabolic syndrome in non-Hispanic White, non-Hispanic Black and Mexican American. Diabetes Metab Syndr. 2020;14(1):3-9. DOI: https://doi.org/10.1016/j.dsx.2019.11.012
11. Beshara A, Cohen E, Goldberg E, Lilos P, Garty M, Krause I. Triglyceride levels and risk of type 2 diabetes mellitus: a longitudinal large study. J Investig Med. 2016;64(2):383-7. DOI: https://doi.org/10.1136/jim-2015-000025
12. Gil Llinás M, Estades Janer P, García Agudo S, González Casquero R, Campos González I. Utilidad en enfermería de diferentes índices antropométricos y analíticos para valorar la existencia de síndrome metabólico con los criterios NCEP ATPIII e IDF en población mediterránea española. Med Balear. 2017;32(1):26-34. DOI: https://doi.org/10.3306/MEDICINABALEAR.32.01.26
13. Fiorentino TV, Marini MA, Succurro E, Andreozzi F, Sesti G. Relationships of surrogate indexes of insulin resistance with insulin sensitivity assessed by euglycemic hyperinsulinemic clamp and subclinical vascular damage. BMJ Open Diab Res Care [Internet]. 2019 [citado 25 Jun 2020];7(1):e000911. Disponible en: https://doi.org/10.1136/bmjdrc-2019-000911
14. Bala C, Gheorghe-Fronea O, Pop D, Pop C, Caloian B, Comsa H, et al. The association between six surrogate insulin resistance indexes and hypertension: A Population-Based Study. Metab Syndr Relat Disord. 2019;17(6):328-33. DOI: https://doi.org/10.1089/met.2018.0122
15. Montano Luna JA, Prieto Díaz VI. Factores de riesgo y enfoque preventivo. En: Sintes RÁ, ed. Medicina General Integral Salud y Medicina. La Habana: Editorial Ciencias Médicas; 2014. p. 56-115.
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