Clinico-epidemiological characterization of infective endocarditis according to administered treatment
Abstract
Introduction: Infective endocarditis, although infrequent, constitutes a highly serious and potentially lethal disease.
Objective: The aim of this study was to describe the clinico-epidemiological behavior of patients diagnosed with infective endocarditis, focusing on the received treatment.
Method: We conducted a descriptive, cross-sectional study with patients diagnosed with infective endocarditis at the Hospital Hermanos Ameijeiras in Havana, Cuba, during the period from January 2006 to December 2019. The sample included 199 patients.
Results: A male predominance (74.9%) was observed, with the most affected age group being between 50 and 69 years (43.7%). Among predisposing factors, immunocompromised patients (25.8%) and those with acquired valvular heart disease (24.7%) showed the highest prevalence in the group treated solely with medical approaches. Conversely, in the group receiving medical-surgical treatment, patients with valve prostheses (27.4%) and cardiac implantable electronic devices (21.7%) were more prominent. Left native valve endocarditis was the most common (62.3%), with staphylococci as the predominant causative agent (27.1%). Cardiac and renal complications were predominant in both treatment groups. Survival during hospitalization reached 79.4%, maintaining similarity in both treatment groups.
Conclusions: The clinical-epidemiological profile was similar in both treatment modalities, emphasizing the predominance of male patients, older age, and the frequent presence of staphylococci as the causative agent. Medical-surgical intervention was primarily directed towards patients with intracardiac electronic devices and in situations with associated complications. Mortality was directly associated with the incidence of complications, irrespective of the administered treatment.
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