TIMI score as a predictor of death in patients with acute myocardial infarction without percutaneous coronary intervention

Abstract

Introduction: Acute myocardial infarction (AMI) is a frequent disorder, associated with high morbidity and mortality; therefore the implementation of risk predictive models is required.
Objective: To determine the value of TIMI score to predict early death risk in patients with ST-elevation AMI.
Method: Patients with a diagnosis of ST-elevation AMI admitted in the intensive care unit (ICU) at Dr. Miguel Enríquez University Hospital were consecutively included. Death risk in ICU was assessed by using a logistic regression model, according to TIMI score at admission.
Results: 115 patients were analyzed. Mean TIMI score was 5.04 (standard deviation 2.7) and the mortality rate was 10.4%. Logistic regression analysis showed that the higher TIMI score was associated with increased death risk in ICU (OR 1.47 [95% CI 1.17-1.83]; p= 0.001); with adequate model calibration (Hosmer-Lemeshow test; X2=5.82; p=0.324), and an area under the receiver-operating characteristic curve of 0.76 [(95% CI 0.60-0.93); p= 0.003].
Conclusions: TIMI score is a good tool to predict the risk of early death in patients with ST-elevation AMI assisted in centers without percutaneous coronary intervention.