Comportamiento de enfermedades cardiovasculares y factores de riesgo coronario en la muerte súbita cardíaca

Liliam G. Cisneros Sánchez; Rosa M. Martínez Peró; Ediunys Carrazana Garcés; Rafaela N. Cuní Mendoza

Authors

Liliam G. Cisneros Sánchez
Rosa M. Martínez Peró
Ediunys Carrazana Garcés
Rafaela N. Cuní Mendoza

Abstract

Introduction: Half of the patients suffering from sudden cardiac death (SCD) have no history of known heart disease. However, most suffer from asymptomatic ischemic heart disease. The most effective approach to prevent SCD in the general population is the accurate quantification of individual risk for ischemic heart disease, followed by control of risk factors.

Objective: To determine the association between some cardiovascular diseases and coronary risk factors with the occurrence of SCD.

Method: An analytical, longitudinal and retrospective study was carried out with 261 patients who died from SCD at the Hospital Enrique Cabrera (Cuba), between January 2014 and March 2018. The possible association between history of cardiovascular disease and coronary risk factors with the occurrence of SCD was sought.

Results: History of coronary artery disease (CAD) (p=0.01) was associated with the appearance of SCD. Age over 70, family history of CAD, and high blood pressure were found to be risk factors associated with the occurrence of SCD. Smoking was a risk factor in the group of patients with no known history of CAD.

Conclusions: Coronary artery disease was the cardiovascular condition most associated with the appearance of SCD. There were both modifiable and non-modifiable coronary risk factors that were associated with the occurrence of SCD.

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References

1. De Asmundis C, Brugada P. Epidemiología de la muerte súbita cardiaca. Rev Esp Cardiol Supl. 2013;13(A):2-6.

2. Priori SG, Blomström-Lundqvist C, Mazzanti A, Blom N, Borggrefe M, Camm J, et al. Guía ESC 2015 sobre el tratamiento de pacientes con arritmias ventriculares y prevención de la muerte súbita cardiaca. Rev Esp Cardiol. 2016;69(2):176.e1-e77.

3. Sarkozy A, Chierchia GB, Rodríguez-Mañero M, Brugada P. Muerte súbita cardiaca en las cardiopatías estructurales. Rev Esp Cardiol Supl. 2013;13(A):7-13.

4. Tamayo Vicente ND, Ochoa Montes LA, Vilches Izquierdo E, González Lugo M, García Ones D. Infarto miocárdico crónico como factor de riesgo de muerte súbita cardíaca. Rev Cuban Invest Bioméd [Internet]. 2015 [citado 9 Oct 2019];34(2):145-56. Disponible en: http://scielo.sld.cu/pdf/ibi/v34n2/ibi05215.pdf

5. Sovari AA, Kocheril AG, Baas AS, Talavera F, Oudiz RJ, Rottman JN, et al. Sudden cardiac death clinical presentation. eMedicine [Internet]. 2014 [citado 9 Oct 2019]. Disponible en: https://emedicine.medscape.com/article/151907-clinical

6. Albert CM, Ruskin JN. Risk stratifiers for sudden cardiac death (SCD) in the community: primary prevention of SCD. Cardiovasc Res. 2001;50(2):186-96.

7. Kaikkonen L. Risk factors for sudden cardiac death from an acute ischemic event in general population: A case-control study [Tesis Doctoral]. Acta Univ Oul [Internet]. Oulu (Finlandia): Oulu University Press; 2009 [citado 10 Oct 2019]. Disponible en: http://jultika.oulu.fi/files/isbn9789514290473.pdf

8. Albert CM. Prediction of sudden cardiac death in patients with coronary heart disease: The challenge ahead. Circ Cardiovasc Imaging. 2008;1(3):175-7.

9. Adabag AS, Luepker RV, Roger VL, Gersh BJ. Sudden cardiac death: epidemiology and risk factors. Nat Rev Cardiol. 2010;7(4):216-25.

10. Bayés de Luna A, Elosua R. Muerte súbita. Rev Esp Cardiol. 2012;65(11):1039-52.

11. Low LS, Kern KB. Importance of coronary artery disease in sudden cardiac death. J Am Heart Assoc [Internet]. 2014 [citado 10 Oct 2019];3(5):e001339. Disponible en: https://doi.org/10.1161/JAHA.114.001339

12. Rodríguez-Reyes H, Muñoz Gutiérrez M, Márquez MF, Pozas Garza G, Asensio Lafuente E, Ortiz Galván F, et al. Muerte súbita cardiaca. Estratificación de riesgo, prevención y tratamiento. Arch Cardiol Mex. 2015;85(4):329-36.

13. Katritsis DG, Gersh BJ, Camm AJ. A Clinical Perspective on Sudden Cardiac Death. Arrhythm Electrophysiol Rev. 2016;5(3):177-82.

14. Luqman N, Sung RJ, Wang CL, Kuo CT. Myocardial ischemia and ventricular fibrillation: pathophysiology and clinical implications. Int J Cardiol. 2007;119(3):283-90.

15. Ochoa Montes LA, González Lugo M, Tamayo Vicente ND, Gómez de Haz HJ, Correa Azahares DP, Miguélez Nodarse R, et al. Epidemiología de la muerte súbita cardíaca. Rev Cuba Hig Epidemiol [Internet]. 2012 [citado 10 Oct 2019];50(1). Disponible en: http://www.revepidemiologia.sld.cu/index.php/hie/article/view/480/410

16. Ferreira-González I. Epidemiología de la enfermedad coronaria. Rev Esp Cardiol. 2014;67(2):139-44.

17. Barrett-Connor E, Khaw K. Family history of heart attack as an independent predictor of death due to cardiovascular disease. Circulation. 1984;69(6):1065-9.

18. López Ramírez M, Ramos Emperador C, Gómez Fernández M, Peña Fernández NE, Fusté Pedroso W, Tamargo Barbeito TO, et al. Factores relacionados con la muerte súbita en pacientes con infarto agudo de miocardio. CorSalud [Internet]. 2017 [citado 10 Oct 2019];9(2):70-9. Disponible en: http://www.revcorsalud.sld.cu/index.php/cors/article/view/149/477

19. Vilches Izquierdo E, Ochoa Montes LA, González Lugo M, Ramos Marrero L, Tamayo Vicente ND, García Ones D, et al. Impacto de la hipertensión arterial esencial y la cardiopatía isquémica en víctimas de muerte cardíaca súbita. Rev Cuban Salud Púb [Internet]. 2016 [citado 12 Oct 2019];42(3). Disponible en: http://www.revsaludpublica.sld.cu/index.php/spu/article/view/662/771

20. Morentin B, Audicana C. Estudio poblacional de la muerte súbita cardiovascular extrahospitalaria: incidencia y causas de muerte en adultos de edad mediana. Rev Esp Cardiol. 2011;64(1):28-34.

21. Messerli FH. Hypertension and sudden cardiac death. Am J Hypertens. 1999;12(12 Pt 3):181-8.

22. Ochoa Montes LA, Yong Medina CA, Calderín Bouza RO, González Lugo M, Miguélez Nodarse R, Vilches Izquierdo E, et al. Factores de riesgo del síndrome metabólico en la muerte súbita cardíaca. Rev Cuban Med [Internet]. 2011 [citado 12 Oct 2019];50(4):426-40. Disponible en: http://scielo.sld.cu/pdf/med/v50n4/med09411.pdf

23. Moreno GM. Definición y clasificación de la obesidad. Rev Med Clin Las Condes. 2012;23(2):124-8.

24. Barroso TA, Marins LB, Alves R, Gonçalves AC, Barroso SG, Rocha GS. Association of central obesity with the incidence of cardiovascular diseases and risk factors. Int J Cardiovasc Sci. 2017;30(5):416-24.

25. Hernanz López P, Peña Lazo A, Coca Díaz M, Suárez Fernández C. Prevalencia de obesidad central y obesidad por índice de masa corporal en un centro de atención primaria. Aten Primaria. 2005;35(7):377-8.

26. Zhang P, Wang R, Gao C, Song Y, Lv X, Jiang L, et al. Types of obesity and its association with the clustering of cardiovascular disease risk factors in Jilin province of China. Int J Environ Res Public Health [Internet]. 2016 [citado 15 Oct 2019];13(7):685. Disponible en: https://doi.org/10.3390/ijerph13070685

27. Adabag S, Huxley RR, Lopez FL, Chen LY, Sotoodehnia N, Siscovick D, et al. Obesity related risk of sudden cardiac death in the atherosclerosis risk in communities study. Heart. 2015;101(3):215-21.

28. Aune D, Schlesinger S, Norat T, Riboli E. Tobacco smoking and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies. Eur J Epidemiol. 2018;33(6):509-21.

29. Vilches Izquierdo E, Ochoa Montes LA, Pernas Sánchez Y, González Lugo M, Ramos Marrero L, Tamayo Vicente ND, et al. Tabaquismo, consumo de alcohol y de café en el espectro de los factores de riesgo para la muerte cardíaca súbita. Rev Cuban Med [Internet]. 2014 [citado 15 Oct 2019];53(3):325-36. Disponible en: http://scielo.sld.cu/pdf/med/v53n3/med09314.pdf

30. Buchanan DM, Arnold SV, Gosch KL, Jones PG, Longmore LS, Spertus JA, et al. Association of smoking status with angina and health-related quality of life after acute myocardial infarction. Circ Cardiovasc Qual Outcomes. 2015;8(5):493-500.

31. Kounka Z, Ortiz C, Sánchez P, Lezcano LE, Romero MJ, Chipayo DA, et al. Diferencias entre el síndrome coronario agudo con y sin elevación del segmento ST en un hospital de área. Rev Esp Cardiol. 2016;69(Supl 1):747 [Resumen].

32. Adabag AS, Therneau TM, Gersh BJ, Weston SA, Roger VL. Sudden death after myocardial infarction. JAMA. 2008;300(17):2022-9.

33. Ren L, Ye H, Wang P, Cui Y, Cao S, Lv S. Comparison of long-term mortality of acute ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome patients after percutaneous coronary intervention. Int J Clin Exp Med. 2014;7(12):5588-92.